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KMID : 0359720150330010036
Journal of the Korean Neurological Association
2015 Volume.33 No. 1 p.36 ~ p.39
Neurosyphilis Presenting with Multiple Cranial Neuropathy
Ryu On-Hwa

Kim Han-A
Lee Joo-Kyung
Kang Shin-Kwang
Kim Sung-Han
Kang Joong-Koo
Abstract
Neurosyphilis can present with various clinical symptoms. We report a patient with multiple cranial neuropathy that, mimicked tuberculosis, but was finally diagnosed as neurosyphilis. A 38-year-old man was admitted due to subacutely progressive hearing loss. Brain MRI revealed multiple dural enhanced masses on contrast-enhanced T1 weighted images. Brain biopsy of the dural enhanced lesion revealed chronic granulomatous inflammation with coagulation necrosis, compatible with syphilitic gumma. Serum venereal disease research laboratory and fluorescent treponemal antibody absorption test results were positive. Treatment with penicillin resolved the patient¡¯s symptom.
KEYWORD
Neurosyphilis, Multiple cranial neuropathy
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